Pub. Date : 2008 Apr
PMID : 18413792
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models. | romidepsin | tumor protein p53 | Homo sapiens |
| 2 | Pretreatment with FK228 enhanced apoptosis in human cancer cells through enhanced transduction of Ad-p53. | romidepsin | tumor protein p53 | Homo sapiens |
| 3 | FK228 also induced hyperacetylation of the p53 protein and specifically enhanced p53-mediated Noxa expression. | romidepsin | tumor protein p53 | Homo sapiens |
| 4 | FK228 also induced hyperacetylation of the p53 protein and specifically enhanced p53-mediated Noxa expression. | romidepsin | tumor protein p53 | Homo sapiens |
| 5 | In human cancer xenograft models, FK228 significantly increased the therapeutic effectiveness of p53 as well as p63 gene therapy. | romidepsin | tumor protein p53 | Homo sapiens |