Pub. Date : 1996 May-Jun
PMID : 18406737
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Five known isoenzymes catalyze the 17beta-hydroxysteroid dehydrogenase reaction that controls the interconversion of estrone and estradiol and of testosterone and androstenedione. | Testosterone | hydroxysteroid 17-beta dehydrogenase 7 | Homo sapiens |
| 2 | Mutations in the 17beta-hydroxysteroid dehydrogenase 3 gene impair the formation of testosterone in the fetal testis and give rise to genetic males with normal male Wolffian duct structures but female external genitalia. | Testosterone | hydroxysteroid 17-beta dehydrogenase 7 | Homo sapiens |
| 3 | The usual mechanism for testosterone formation in affected individuals at puberty appears to be conversion of androstenedione to testosterone in extraglandular tissues by one or more of the unaffected 17beta-hydroxysteroid dehydrogenase isoenzymes. | Testosterone | hydroxysteroid 17-beta dehydrogenase 7 | Homo sapiens |