Title : Glucocorticoids induce human glycoprotein hormone alpha-subunit gene expression in the gonadotrope.

Pub. Date : 2008 Jul

PMID : 18403486






1 Functional Relationships(s)
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1 Furthermore, overexpression of the homeobox factor, Distal-less 3 that regulates this gene in placental cells through a site partially overlapping GRE2, blocks Dex induction of alphaGSU in gonadotrope cells, indicating that placenta-specific expression of Dlx3 may interfere with GR, resulting in repression in placental cells vs. induction in gonadotrope cells. Dexamethasone distal-less homeobox 3 Homo sapiens