Title : Rhodopsin regeneration is accelerated via noncovalent 11-cis retinal-opsin complex--a role of retinal binding pocket of opsin.

Pub. Date : 2008 Jul-Aug

PMID : 18399914






2 Functional Relationships(s)
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Protein Name
Organism
1 The regeneration of bovine rhodopsin from its apoprotein opsin and the prosthetic group 11-cis retinal involves the formation of a retinylidene Schiff base with the epsilon-amino group of the active lysine residue of opsin. retinylidene schiff base rhodopsin Bos taurus
2 These results are interpreted by the Matsumoto and Yoshizawa (Nature 258 [1975] 523) model of rhodopsin regeneration in which the 11-cis retinal chromophore binds first to opsin through the beta-ionone ring, followed by the slow formation of the retinylidene Schiff base in a restricted space. retinylidene schiff base rhodopsin Bos taurus