Title : Stability of the Hsp90 inhibitor 17AAG hydroquinone and prevention of metal-catalyzed oxidation.

Pub. Date : 2008 Dec

PMID : 18393300






1 Functional Relationships(s)
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1 The hydroquinone derivative of 17AAG, 17AAG hydroquinone (17AAGH(2)), is considerably more water soluble and since we previously demonstrated that 17AAGH(2) was a more potent Hsp90 inhibitor than its parent quinone, it is a good candidate for clinical use and is currently in clinical trials. quinone heat shock protein 90 alpha family class A member 1 Homo sapiens