Title : A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure.

Pub. Date : 2008 May

PMID : 18391101






2 Functional Relationships(s)
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1 The CYP4A11 CC/TC genotype was significantly associated with a reduction in 20-hydroxyeicosatetraenoic acid excretion but was not associated with blood pressure. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily A member 11 Homo sapiens
2 We have demonstrated for the first time in humans that polymorphisms of the CYP4F2 and CYP4A11 genes have opposite effects on 20-hydroxyeicosatetraenoic acid excretion. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily A member 11 Homo sapiens