Pub. Date : 1991 Oct 28
PMID : 1838582
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The vasopressin receptor of the blood-brain barrier in the rat hippocampus is linked to calcium signalling. | Calcium | arginine vasopressin | Rattus norvegicus |
| 2 | We determined the effect of arginine vasopressin (AVP) on the intracellular free calcium concentration [Ca2+]i in endothelial cells of isolated hippocampal microvessels of rats, using the fura-2 fluorescence technique. | Calcium | arginine vasopressin | Rattus norvegicus |
| 3 | AVP administration caused a rapid and transient rise of cytosolic free calcium which was absent after extracellular calcium was removed, and could be blocked with the vasopressin V1 receptor antagonist, d(CH2)5 Tyr(Me)AVP. | Calcium | arginine vasopressin | Rattus norvegicus |
| 4 | AVP administration caused a rapid and transient rise of cytosolic free calcium which was absent after extracellular calcium was removed, and could be blocked with the vasopressin V1 receptor antagonist, d(CH2)5 Tyr(Me)AVP. | Calcium | arginine vasopressin | Rattus norvegicus |
| 5 | Our results, therefore, demonstrate the presence of a calcium-signalling, i.e. V1 vasopressin receptor at the blood-brain barrier in the hippocampus of the rat. | Calcium | arginine vasopressin | Rattus norvegicus |