Title : The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast.

Pub. Date : 2008 Apr 1

PMID : 18381895






1 Functional Relationships(s)
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1 Here we show that the mitochondrial components of the malate-aspartate NADH shuttle (Mdh1 [malate dehydrogenase] and Aat1 [aspartate amino transferase]) and the glycerol-3-phosphate shuttle (Gut2, glycerol-3-phosphate dehydrogenase) are novel longevity factors in the CR pathway in yeast. NAD glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C