Title : Protective effects of interrupting the binding of calmodulin to mutant huntingtin.

Pub. Date : 2008 Apr

PMID : 18379433






1 Functional Relationships(s)
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1 Carbachol-stimulated release of intracellular calcium is significantly higher in cells expressing N-terminal mutant huntingtin and TG2 compared with vector-transfected cells; expression of either CaM-center or CaM-overlap in these cells returned the levels of carbachol-stimulated intracellular calcium release to control values. Calcium huntingtin Homo sapiens