Title : Changes in the gene expression of C-myc and CD38 in HL-60 cells during differentiation induced by nicotinic acid-related compounds.

Pub. Date : 2008 Mar

PMID : 18323656






1 Functional Relationships(s)
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1 Nicotinamide and nicotinamide N-oxide drastically decreased c-myc expression, but isonicotinic acid had no effect, suggesting that these compounds differentiate HL-60 to granulocytes through different pathways. nicotinamide N-oxide MYC proto-oncogene, bHLH transcription factor Homo sapiens