Title : Central estrogen-like effect of genistein on growth hormone secretion in the ewe.

Pub. Date : 2007

PMID : 18320719






3 Functional Relationships(s)
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1 In 17beta-estradiol-infused animals, a significant increase in GH concentration was noted during the first two hours of the infusion, in comparison with vehicle-infused and also in comparison with genistein-infused ewes. Estradiol growth hormone 1 Homo sapiens
2 Although a gradual increase in basic GH secretion continued in all treated groups during the afternoon and evening, mean plasma GH concentrations in genistein- and 17beta-estradiol-infused ewes were still significantly higher than in the vehicle-infused. Estradiol growth hormone 1 Homo sapiens
3 In conclusion, genistein as 17beta-estradiol, is an effective stimulator of GH secretion in ewes and may exert its effect at the level of the CNS. Estradiol growth hormone 1 Homo sapiens