Title : Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells.

Pub. Date : 2008 Jul 3

PMID : 18317449






1 Functional Relationships(s)
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1 A quantitative comparative analysis demonstrates that inhibiting DNA methyltransferases using 5-aza-2"-deoxycytidine or specific disruption of DNMT1 by small interfering RNAs and treatment with the histone-deacetylase inhibitor trichostatin A enabled ERalpha-mediated hormone-dependent expression of endogenous PR. trichostatin A estrogen receptor 1 Homo sapiens