Title : Inhibition of dipeptidyl peptidase IV with sitagliptin (MK0431) prolongs islet graft survival in streptozotocin-induced diabetic mice.

Pub. Date : 2008 May

PMID : 18299314






1 Functional Relationships(s)
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1 Residual beta-cell mass was extremely low in STZ-induced diabetic mice, and although active GLP-1 levels were increased by the MK0431 diet, there were no significant effects on glycemic control. Sitagliptin Phosphate glucagon Mus musculus