Pub. Date : 2008 Jun
PMID : 18298671
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nuclear localization of the mutant protein phosphatase abi1 is required for insensitivity towards ABA responses in Arabidopsis. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 2 | ABI1, a protein phosphatase 2C, is a key component of ABA signal transduction in Arabidopsis that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 3 | ABI1, a protein phosphatase 2C, is a key component of ABA signal transduction in Arabidopsis that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 4 | The abi1-1 mutation, so far the only characterized dominant allele for ABI1, impairs ABA responsitivity in both seeds and vegetative tissues. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 5 | The abi1-1 mutation, so far the only characterized dominant allele for ABI1, impairs ABA responsitivity in both seeds and vegetative tissues. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 6 | We show that there is an essential requirement for nuclear localization of abi1 to confer insensitivity towards ABA responses. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 7 | Transient analyses in protoplasts revealed a strict dependence of wild-type ABI1 and mutant abi1 on a functional nuclear localization sequence (NLS) for regulating ABA-dependent gene expression. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 8 | Transient analyses in protoplasts revealed a strict dependence of wild-type ABI1 and mutant abi1 on a functional nuclear localization sequence (NLS) for regulating ABA-dependent gene expression. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 9 | Arabidopsis lines with ectopic expression of various abi1 forms corroborated the necessity of a functional NLS to control ABA sensitivity. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 10 | Disruption of the NLS function in abi1 rescued ABA-controlled gene transcription to wild-type levels, but also attenuated abi1-conferred insensitivity towards ABA during seed germination, root growth and stomatal movement. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |
| 11 | Thus, abi1-1 acts as a hypermorphic allele, and ABI1 reprograms sensitivity towards ABA in the nucleus. | alisol B 23-acetate | Protein phosphatase 2C family protein | Arabidopsis thaliana |