Title : The role of arginine-vasopressin for pineal melatonin synthesis in the rat: involvement of vasopressinergic receptors.

Pub. Date : 1991 Feb 11

PMID : 1829510






3 Functional Relationships(s)
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1 The nocturnal intra-arterial application of dDAVP mimicked the inhibitory effect of AVP on the activity of the rate-limiting enzyme for pineal melatonin synthesis, N-acetyltransferase (NAT), in both rat strains. Melatonin arginine vasopressin Rattus norvegicus
2 These results reveal that at least two mechanisms mediate the influence of AVP on pineal melatonin synthesis. Melatonin arginine vasopressin Rattus norvegicus
3 The present results support the idea of a modulatory role of AVP and its metabolites in the generation and maintenance of the circadian melatonin rhythm in mammals. Melatonin arginine vasopressin Rattus norvegicus