Title : Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling.

Pub. Date : 2008 May 15

PMID : 18289623






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mafosfamide caused p53 stabilization by phosphorylation of Ser15, 20 and 37, and activation of ATM/ATR and Chk1/Chk2. mafosfamide checkpoint kinase 1 Homo sapiens