Title : Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.

Pub. Date : 2008 May

PMID : 18287539






1 Functional Relationships(s)
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1 We also provide evidence that ARV1 deletion and mutations in other proteins involved in GPI anchor synthesis affect inositol phosphorylceramide synthesis as well as the intracellular distribution and amounts of sterols, suggesting a role of GPI anchor synthesis in lipid flow from the ER. Sterols sterol homeostasis protein ARV1 Saccharomyces cerevisiae S288C