Title : Induction of apoptosis in human leukaemia HL-60 cells by furanone-coumarins from Murraya siamensis.

Pub. Date : 2008 Mar

PMID : 18284820






4 Functional Relationships(s)
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1 In addition, treatment with murrayacoumarin B stimulated the activities of caspase-9 and caspase-3, and caspase-9 and caspase-3 inhibitors suppressed the apoptosis induced by murrayacoumarin B. murrayacoumarin B caspase 3 Homo sapiens
2 In addition, treatment with murrayacoumarin B stimulated the activities of caspase-9 and caspase-3, and caspase-9 and caspase-3 inhibitors suppressed the apoptosis induced by murrayacoumarin B. murrayacoumarin B caspase 3 Homo sapiens
3 In addition, treatment with murrayacoumarin B stimulated the activities of caspase-9 and caspase-3, and caspase-9 and caspase-3 inhibitors suppressed the apoptosis induced by murrayacoumarin B. murrayacoumarin B caspase 3 Homo sapiens
4 These results suggest that murrayacoumarin B induced apoptosis in HL-60 cells through activation of the caspase9/caspase-3 pathway triggered by mitochondrial dysfunction. murrayacoumarin B caspase 3 Homo sapiens