Pub. Date : 2008 Feb
PMID : 18281755
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Recent studies in this area have demonstrated various mechanisms involved in the anti-tumor activity of docetaxel: (1) efflux (p-glycoprotein), (2) metabolism (CYP3A4), (3) beta-tubulin (isotype class I and III), (4) cell cycle (HER2, BRCA1), (5) apoptosis (p53, Bcl-2, thioredoxin), and (6) cell proliferation (MIB-1, nuclear grade). | Docetaxel | BRCA1 DNA repair associated | Homo sapiens |