Pub. Date : 2008 Apr 15
PMID : 18275859
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In these Pten-deleted MEFs, the basal levels of reactive oxygen species (ROS) were increased, and both the basal level and the ROS-induced oxidative damage of DNA were increased, as evidenced by increased levels of hydrogen peroxide (H2O2), superoxide anion, 8-hydroxy-2"-deoxyguanosine, and DNA double-strand breaks. | Hydrogen Peroxide | phosphatase and tensin homolog | Mus musculus |
| 2 | In these Pten-deleted MEFs, the basal levels of reactive oxygen species (ROS) were increased, and both the basal level and the ROS-induced oxidative damage of DNA were increased, as evidenced by increased levels of hydrogen peroxide (H2O2), superoxide anion, 8-hydroxy-2"-deoxyguanosine, and DNA double-strand breaks. | Hydrogen Peroxide | phosphatase and tensin homolog | Mus musculus |
| 3 | We further show that Pten deletion is correlated with resistance to H2O2-induced expression of several antioxidants. | Hydrogen Peroxide | phosphatase and tensin homolog | Mus musculus |