Title : Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.

Pub. Date : 2008 Feb 26

PMID : 18268143






1 Functional Relationships(s)
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1 CONCLUSIONS: These results demonstrate that endothelium-specific GTPCH I overexpression abrogates O2(-) production and preserves eNOS phosphorylation, which results in preserved structural and functional integrity of resistance mesenteric arteries and lowered blood pressure in low-renin hypertension. Superoxides GTP cyclohydrolase 1 Mus musculus