Title : Targeting lipid metabolism in the treatment of hepatitis C virus infection.

Pub. Date : 2008 Feb 1

PMID : 18248300






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Myriocin suppressed replication of both a genotype 1b subgenomic HCV replicon (Huh7/Rep-Feo) and genotype 2a infectious HCV (JFH-1 HCV) in a dose-dependent manner (for subgenomic HCV-1b, maximum of 79% at 1000 nmol/L; for genomic HCV-2a, maximum of 40% at 1000 nmol/L). thermozymocidin MIR7-3 host gene Homo sapiens
2 Combination treatment with myriocin and IFN or myriocin and simvastatin attenuated HCV RNA replication synergistically in Huh7/Rep-Feo cells. thermozymocidin MIR7-3 host gene Homo sapiens
3 Combination treatment with myriocin and IFN or myriocin and simvastatin attenuated HCV RNA replication synergistically in Huh7/Rep-Feo cells. thermozymocidin MIR7-3 host gene Homo sapiens