Title : Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine beta-synthase and apolipoprotein A-I.

Pub. Date : 2008 Mar

PMID : 18224302






2 Functional Relationships(s)
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1 Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine beta-synthase and apolipoprotein A-I. Simvastatin apolipoprotein A-I Mus musculus
2 In conclusion, the results of this study demonstrate that the use of simvastatin can improve blood pressure control in mice with elevated homocysteinemia and low levels of apoA-I, and this effect is mediated by mechanisms independent of plasma lipids and related to nitric oxide levels. Simvastatin apolipoprotein A-I Mus musculus