Title : Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice.

Pub. Date : 2008 Mar

PMID : 18204078






1 Functional Relationships(s)
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1 Many studies using mammalian cellular and subcellular systems have demonstrated that polycyclic aromatic hydrocarbons, including benzo[a]pyrene (BaP), are metabolically activated by cytochrome P450s (CYPs). Polycyclic Aromatic Hydrocarbons prohibitin 2 Homo sapiens