Pub. Date : 2007 Dec
PMID : 18202523
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gd treatment significantly suppressed styrene-inducible cytochrome P4502B1 (CYP2B1), CYP2B2, CYP2E1, and CYP3A2 mRNA expressions to 48.6%, 69.8%, 61.1%, and 38.5%, accompanying with the reduction of proteins expression to 1.42%, 31.2%, 21.1% and 21.1%, respectively, compared with styrene alone treatment. | Styrene | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 2 | In summary, Gd suppressed styrene-inducible expression of not only CYP2B1 but also several forms of P450 at both the mRNA and protein levels, along with attenuation of styrene-caused liver damage. | Styrene | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |