Title : Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule.

Pub. Date : 2008 Mar

PMID : 18199679






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Celastrol activated the yeast Yap1 oxidant defense transcription factor via the carboxy-terminal redox center that responds to electrophilic compounds. celastrol DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C