Title : Calcium channel blockade inhibits platelet activating factor production by human umbilical vein endothelial cells.

Pub. Date : 1991 Dec

PMID : 1819708






1 Functional Relationships(s)
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1 Results (triplicate experiments, * P less than 0.05 vs buffer, P less than 0.05 vs thrombin) demonstrate that pre-incubation with calcium channel blocker markedly inhibits thrombin-induced PAF production (verapamil:buffer 273 +/- 122, thrombin 10,735 +/- 1524*, thrombin + verapamil 178 +/- 91 cpm/plate; diltiazem:buffer 1097 +/- 581, thrombin 15,283 +/- 2661*, thrombin + diltiazem 280 +/- 56 cpm/plate). Verapamil PCNA clamp associated factor Homo sapiens