Title : 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.

Pub. Date : 2008 Oct

PMID : 18193228






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PT-262 induced the loss of mitochondrial membrane potential and elevated the caspase-3 activation and apoptosis. Platinum caspase 3 Homo sapiens