Title : Lobeline effects on tonic and methamphetamine-induced dopamine release.

Pub. Date : 2008 Mar 15

PMID : 18191815






2 Functional Relationships(s)
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1 Lobeline caused release of [(3)H]dopamine to a similar extent as reserpine (VMAT-2 inhibitor), but was less efficacious than methamphetamine or dopamine. Lobeline solute carrier family 18 member A2 Homo sapiens
2 These results suggest that lobeline has unique properties at the DAT and VMAT-2 which may make it useful as a pharmacotherapeutic to treat methamphetamine abuse. Lobeline solute carrier family 18 member A2 Homo sapiens