Title : YFa, a chimeric opioid peptide, induces kappa-specific antinociception with no tolerance development during 6 days of chronic treatment.

Pub. Date : 2008 May 15

PMID : 18183621






1 Functional Relationships(s)
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1 Our previous study showed that YGGFMKKKFMRFamide (YFa), a chimeric peptide of Met-enkephalin, and Phe-Met-Arg-Phe-NH2 induced naloxone-reversible antinociception and attenuated the development of tolerance to morphine analgesia. Morphine proopiomelanocortin Homo sapiens