Title : Effect of an antiretroviral regimen containing ritonavir boosted lopinavir on intestinal and hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected patients.

Pub. Date : 2008 Jul

PMID : 18183034






1 Functional Relationships(s)
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1 In CYP2D6 extensive metabolizers, the plasma ratio AUC(dextromethorphan)/AUC(dextrorphan) increased to 2.92-fold (2.31-3.69). Dextromethorphan cytochrome P450 family 2 subfamily D member 6 Homo sapiens