Title : PC12 cells as a window for the differentiation of neural crest into adrenergic nerve ending and adrenal medulla.

Pub. Date : 1991

PMID : 1817165






2 Functional Relationships(s)
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1 Like the observations on adrenergic neurones, non-selective and selective MAO-A inhibitors potentiate the catecholamine-releasing property of tyramine in PC12 cells. Catecholamines monoamine oxidase A Rattus norvegicus
2 In the final analysis the inter-relationship between MAO-A activity and the presence of tyramine-releasable pool of catecholamines in adrenergic neurons and PC12 cells may have a genetic basis and could be important in illuminating the differentiation of neural crest into adrenergic neurones and adrenal medulla on the one hand and chromaffin cells to PC12 cells on the other. Catecholamines monoamine oxidase A Rattus norvegicus