Pub. Date : 2008 Jan
PMID : 18166786
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | DESIGN AND METHODS: We studied the in vitro activity and mechanism of action of bortezomib on both cell lines and fresh cells from 28 AML patients including CD34(+) and CD34(-) cases. | Bortezomib | CD34 molecule | Homo sapiens |
2 | DESIGN AND METHODS: We studied the in vitro activity and mechanism of action of bortezomib on both cell lines and fresh cells from 28 AML patients including CD34(+) and CD34(-) cases. | Bortezomib | CD34 molecule | Homo sapiens |
3 | The apoptotic activity of bortezomib on fresh CD34(+) blast cells from patients was similar to that observed on CD34(-)blast cells. | Bortezomib | CD34 molecule | Homo sapiens |
4 | Importantly, bortezomib was significantly more active than doxorubicin in the immature CD34(+) cells, while there were no differences in its action on CD34(-) cells. | Bortezomib | CD34 molecule | Homo sapiens |