Pub. Date : 2008 May 15
PMID : 18166199
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of HU on SMN2 gene expression and clinical manifestations was evaluated. | Hydroxyurea | survival of motor neuron 2, centromeric | Homo sapiens |
| 2 | CONCLUSIONS: Treating with HU enhanced SMN2 gene expression in SMA cells and showed slight trend towards improvement in some clinical outcome measures in SMA patients which suggests HU may be safe to use in SMA patients but larger randomized, placebo-controlled, double-blind trials are needed to further investigate its efficacy. | Hydroxyurea | survival of motor neuron 2, centromeric | Homo sapiens |