Pub. Date : 2008 Feb 15
PMID : 18163430
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study investigated the contribution of androgen receptor (AR) in the combined effect of TGF-beta and dihydrotestosterone (DHT), on regulation of apoptosis and AR- and TGF-beta mediated transcriptional activity in human prostate cancer cells. | Dihydrotestosterone | transforming growth factor beta 1 | Homo sapiens |
| 2 | This study investigated the contribution of androgen receptor (AR) in the combined effect of TGF-beta and dihydrotestosterone (DHT), on regulation of apoptosis and AR- and TGF-beta mediated transcriptional activity in human prostate cancer cells. | Dihydrotestosterone | transforming growth factor beta 1 | Homo sapiens |
| 3 | The apoptotic response to DHT/TGFbeta treatment was correlated with AR cellular distribution and the AR interaction with TGF-beta intracellular effector Smad4. | Dihydrotestosterone | transforming growth factor beta 1 | Homo sapiens |
| 4 | TGF-beta1 induced transcriptional activity enhanced by DHT in both cell lines (LNCaP-TbetaRII and PC-3-AR) via AR-Smad4 interaction. | Dihydrotestosterone | transforming growth factor beta 1 | Homo sapiens |