Title : Regulation of cholesterol biosynthesis in sitosterolemia: effects of lovastatin, cholestyramine, and dietary sterol restriction.

Pub. Date : 1991 Dec

PMID : 1816322






1 Functional Relationships(s)
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1 The rates of conversion of acetate to cholesterol by mononuclear leukocytes were subnormal in all homozygous and heterozygous subjects and correlated with markedly reduced microsomal 3-hydroxy-3-methylglutaryl co-enzyme A (HMG-CoA) reductase activity. Acetates 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens