Title : Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis.

Pub. Date : 2008 Mar 21

PMID : 18160398

1 Functional Relationships(s)
Compound Name
Protein Name
1 We further present evidence that the effect of PAK1 on the respiratory burst is mediated through phosphorylation of p47(Phox), and we show that expression of a p47(Phox) (S303D/S304D/S320D) mutant, which mimics phosphorylation by PAK1, induced basal superoxide generation in vivo. Superoxides pleckstrin Homo sapiens