Title : Caspase 3 activation in human spermatozoa in response to hydrogen peroxide and progesterone.

Pub. Date : 2008 Oct

PMID : 18155705






1 Functional Relationships(s)
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1 Pretreatment of spermatozoa with Ru360, to block the calcium uptake into mitochondria, also was able to decrease the activation of caspase-3 and phosphatidylserine exposure that was stimulated by either H2O2 or P. CONCLUSION(S): These findings suggest that H2O2- and P-induced mitochondrial apoptosis is dependent on calcium signaling. Calcium caspase 3 Homo sapiens