Title : Defective trafficking and localization of mutated transferrin receptor 2: implications for type 3 hereditary hemochromatosis.

Pub. Date : 2008 Feb

PMID : 18094142






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Transferrin receptor 2 (TfR2), a homologue of transferrin receptor 1 (TfR1), is a key molecule involved in the regulation of iron homeostasis. Iron transferrin receptor 2 Homo sapiens
2 Transferrin receptor 2 (TfR2), a homologue of transferrin receptor 1 (TfR1), is a key molecule involved in the regulation of iron homeostasis. Iron transferrin receptor 2 Homo sapiens
3 Mutations in TfR2 result in iron overload with similar features to HFE-associated hereditary hemochromatosis. Iron transferrin receptor 2 Homo sapiens
4 The precise role of TfR2 in iron metabolism and the functional consequences of disease-causing mutations have not been fully determined. Iron transferrin receptor 2 Homo sapiens