Title : Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1.

Pub. Date : 2008 Feb 22

PMID : 18093972






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Levels of HIPK2 were increased by UV irradiation and cisplatin treatment, thereby implying the degradation of HIPK2 in cells under normal conditions. Cisplatin homeodomain interacting protein kinase 2 Homo sapiens
2 Levels of HIPK2 were increased by UV irradiation and cisplatin treatment, thereby implying the degradation of HIPK2 in cells under normal conditions. Cisplatin homeodomain interacting protein kinase 2 Homo sapiens
3 The ubiquitination and degradation of HIPK2 by WSB-1 was inhibited completely via the administration of DNA damage reagents, including Adriamycin and cisplatin. Cisplatin homeodomain interacting protein kinase 2 Homo sapiens