Title : The effect of mood stabilizer lithium on expression and activity of glutathione s-transferase isoenzymes.

Pub. Date : 2008 Jan 24

PMID : 18082333






1 Functional Relationships(s)
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1 Since GST conjugates glutathione, the major antioxidant in brain, with a variety of oxidized products to form nontoxic products, and plays an important role in cellular protection against oxidative stress, our findings suggest that lithium selectively targets GST isoenzymes in order to produce neuroprotective effects against oxidative stress. Glutathione hematopoietic prostaglandin D synthase Rattus norvegicus