Pub. Date : 2008 Feb
PMID : 18080754
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We previously showed that cultured mouse cerebellar granule cells during incubation in glutamine-replete medium respond to 45 mM [K(+)](e) after 20 and 60 min incubation with extracellular-signal regulated kinase 1 and 2 (ERK(1/2)) phosphorylation which is mainly, but probably not exclusively, secondary to glutamate release and transactivation of epidermal growth factor (EGF) receptors. | Glutamic Acid | mitogen-activated protein kinase 3 | Mus musculus |
| 2 | Addition of 50 microM glutamate to the cells caused ERK(1/2) phosphorylation already after 5 min most of which was sensitive to PKC inhibition although a minor part was PKC inhibition-resistant. | Glutamic Acid | mitogen-activated protein kinase 3 | Mus musculus |