Pub. Date : 1991 Dec
PMID : 1808024
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present study was carried out to evaluate the in vitro effects of mammalian gonadotropin-releasing hormone (mGnRH) on the production of prostaglandin F2 alpha (PGF2 alpha) and sex steroids (progesterone, androgens, and 17 beta-estradiol) by the interrenal gland of male and female Rana esculenta during three different periods of the sexual annual cycle. | Estradiol | gonadotropin releasing hormone 1 | Mus musculus |
| 2 | Progesterone and androgens were undetectable, while 17 beta-estradiol was significantly increased by mGnRH in interrenals incubated during the postreproductive period in both sexes. | Estradiol | gonadotropin releasing hormone 1 | Mus musculus |
| 3 | In addition, the simultaneous increase in PGF2 alpha and estradiol from postreproductive cultured interrenals support the notion that mGnRH-induced estradiol synthesis is mediated through PGF2 alpha formation. | Estradiol | gonadotropin releasing hormone 1 | Mus musculus |
| 4 | In addition, the simultaneous increase in PGF2 alpha and estradiol from postreproductive cultured interrenals support the notion that mGnRH-induced estradiol synthesis is mediated through PGF2 alpha formation. | Estradiol | gonadotropin releasing hormone 1 | Mus musculus |
| 5 | This finding, taken together with other previous studies, strongly suggests that the end of the breeding period in R. esculenta depends on GnRH-induced PGF2 alpha-mediated enhancement of estradiol synthesis in a steroidogenetic organ (probably interrenals). | Estradiol | gonadotropin releasing hormone 1 | Mus musculus |