Pub. Date : 2007 Dec
PMID : 18077578
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We recently demonstrated that melatonin, N-acetylserotonin (NAS), and N-acetyldopamine (NAD) attenuate the synthesis of lipopolysaccharide (LPS)-stimulated tumor necrosis factor-alpha (TNF-alpha) and the generation of oxidant radicals. | N-acetylserotonin | tumor necrosis factor | Homo sapiens |
| 2 | We recently demonstrated that melatonin, N-acetylserotonin (NAS), and N-acetyldopamine (NAD) attenuate the synthesis of lipopolysaccharide (LPS)-stimulated tumor necrosis factor-alpha (TNF-alpha) and the generation of oxidant radicals. | N-acetylserotonin | tumor necrosis factor | Homo sapiens |
| 3 | We recently demonstrated that melatonin, N-acetylserotonin (NAS), and N-acetyldopamine (NAD) attenuate the synthesis of lipopolysaccharide (LPS)-stimulated tumor necrosis factor-alpha (TNF-alpha) and the generation of oxidant radicals. | N-acetylserotonin | tumor necrosis factor | Homo sapiens |
| 4 | We recently demonstrated that melatonin, N-acetylserotonin (NAS), and N-acetyldopamine (NAD) attenuate the synthesis of lipopolysaccharide (LPS)-stimulated tumor necrosis factor-alpha (TNF-alpha) and the generation of oxidant radicals. | N-acetylserotonin | tumor necrosis factor | Homo sapiens |
| 5 | Incubating THP-1-derived monocytes with rising concentrations of NAS, NAD, NMD, or 4-O-MD markedly decreased LPS-stimulated TNF-alpha production, which was dose dependent and on the order of 96%-98%. | N-acetylserotonin | tumor necrosis factor | Homo sapiens |
| 6 | Our results indicated that the inhibitory effect of NAS, NAD, NMD, or 4-O-MD on LPS-induced TNF-alpha production and FeCl(2)-stimulated lipid peroxidation is robust and dose dependent. | N-acetylserotonin | tumor necrosis factor | Homo sapiens |