Title : Genetic regulation of dihydropyrimidinase and its possible implication in altered uracil catabolism.

Pub. Date : 2007 Nov

PMID : 18075467






1 Functional Relationships(s)
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1 There, however, remain a number of patients presenting with 5-fluorouracil-associated toxicity despite normal DPD enzyme activity, suggesting possible deficiencies in dihydropyrimidinase (DHP), encoded by the DPYS gene, and/or beta-ureidopropionase (BUP-1), encoded by the UPB1 gene. Fluorouracil dihydropyrimidinase Homo sapiens