Title : Modulation of network-driven, GABA-mediated giant depolarizing potentials by SDF-1alpha in the developing hippocampus.

Pub. Date : 2008

PMID : 18073458






2 Functional Relationships(s)
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1 We also showed that endogenous SDF-1 exerts a tonic inhibitory action on GDPs in the developing hippocampus. gdps C-X-C motif chemokine ligand 12 Rattus norvegicus
2 As SDF-1/CXCR4 are highly expressed in the developing brain and GDPs are involved in activity-dependent synapse formation and functioning, the inhibitory action of SDF-1alpha on GDPs may reflect a potential mechanism for chemokine regulation of neural development in early neonatal life. gdps C-X-C motif chemokine ligand 12 Rattus norvegicus