Pub. Date : 2008 May 15
PMID : 18071310
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Hsp90-inhibitor geldanamycin abrogates G2 arrest in p53-negative leukemia cell lines through the depletion of Chk1. | geldanamycin | tumor protein p53 | Homo sapiens |
2 | These results suggest that abrogation of G2 checkpoint by GM may play a central role in sensitizing p53-negative tumor cells to DNA-damaging and decatenation-inhibiting agents. | geldanamycin | tumor protein p53 | Homo sapiens |