Title : Strategies for administration of tissue plasminogen activator.

Pub. Date : 1991 Apr

PMID : 1806764






1 Functional Relationships(s)
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1 The major findings in clinical evaluation for acute myocardial infarction to date include (1) substantial mortality reduction and improvement in cardiac function; (2) an excess of serious bleeding complications at high doses (150 mg) of t-PA; (3) rapid infarct vessel recanalization with an accelerated "front-loaded" regimen; (4) the importance of conjunctive intravenous heparin; and (5) the potential for new, combined plasminogen activator therapies. Heparin chromosome 20 open reading frame 181 Homo sapiens