Title : Molecular evolution of Keap1. Two Keap1 molecules with distinctive intervening region structures are conserved among fish.

Pub. Date : 2008 Feb 8

PMID : 18057000






3 Functional Relationships(s)
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1 Similarly, cysteine residues corresponding to Cys-273 and Cys-288 in the intervening region of mouse Keap1, which are essential for the repression of Nrf2 activity in cultured cells, are conserved among Keap1 orthologs in vertebrates and invertebrates, except fish. Cysteine nuclear factor, erythroid derived 2, like 2 Mus musculus
2 Similarly, cysteine residues corresponding to Cys-273 and Cys-288 in the intervening region of mouse Keap1, which are essential for the repression of Nrf2 activity in cultured cells, are conserved among Keap1 orthologs in vertebrates and invertebrates, except fish. Cysteine nuclear factor, erythroid derived 2, like 2 Mus musculus
3 Similarly, cysteine residues corresponding to Cys-273 and Cys-288 in the intervening region of mouse Keap1, which are essential for the repression of Nrf2 activity in cultured cells, are conserved among Keap1 orthologs in vertebrates and invertebrates, except fish. Cysteine nuclear factor, erythroid derived 2, like 2 Mus musculus