Title : The IL-4Ralpha pathway in macrophages and its potential role in silica-induced pulmonary fibrosis.

Pub. Date : 2008 Mar

PMID : 18056481






1 Functional Relationships(s)
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1 In the in vitro assay, a significant increase in TC activation, as defined by surface markers and cytokines, was observed in the cultures containing the silica-exposed macrophages in wild-type and IL-4Ralpha(-/-) mice, with one exception: IL-4Ralpha(-/-) BMdM were unable to induce an increase in IL-13. Silicon Dioxide interleukin 13 Mus musculus